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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are typically characterized by a focus on practical aspects of the study design, including the recruitment process and consent in adherence, as well as the use of commonly available equipment.

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A practical trial that employs a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is essential for pragmatic trials to be able to prove their validity, and it also helps to reduce the chance of bias in the results. However too much heterogeneity could result in issues with the design of the trial.

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The aim of pragmatic trials is to mimic real-life scenarios and gain the highest level of validity externally. They are typically commissioned by policy makers and practitioners to aid in their decision-making. They can also be a great way to identify the causality between an intervention and <a href="프라그마틱”>https://clinfowiki.win/wiki/Post:8_Tips_To_Enhance_Your_Pragmatic_Free_Trial_Game”>프라그마틱 불법 its results. However, they shouldn’t be used in lieu for explanation trials.

The concept of pragmatism is controversial, and there are questions regarding whether pragmatic trials could replace tests for <a href="프라그마틱”>https://mozillabd.science/wiki/Mcleanguthrie7761″>프라그마틱 슬롯체험 explanations or if they should serve as a complement to them. Schwartz and <a href="프라그마틱”>https://www.demilked.com/author/sealsmile1/”>프라그마틱 슬롯 체험 Lellouch1 proposed the distinction between explanation studies, which prove the validity of a physiological or clinical hypothesis, and pragmatic trials that aid in the decision-making process for policy and practice. They also proposed the framework for pragmatic trials, dubbed PRECIS.2 This tool was designed to define the characteristics of a pragmatic trial which includes the recruitment process, the design and delivery of the intervention, and follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, limited to randomized controlled trials (RCTs) resulted in 34 articles, shown in red in Figure 2. This is an indication that the health science community is becoming more acquaint to the issue of pragmatics. It is important to keep in mind that the majority of these studies were conducted in primary care settings.